Muscular Subaortic Stenosis

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Muscular Subaortic Stenosis

Left ventricular ejection time was correlated with the intraventricular pressure gradient in 35 cases of muscular subaortic stenosis in which simultaneous aortic and left ventricular pressure recordings were available. Ejection times were corrected for heart rate by dividing them by the square root of the cycle length. There was a direct relation between the degree of prolongation of the ejecti...

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The Electrocardiogram in Muscular Subaortic Stenosis

FOLLOWING Brock's' recognition that hypertrophied muscle in the left ventricular outflow tract could obstruct left ventricular outflow, much interest has centered on the nature of this hypertrophy. Initial reports suggested that concentric hypertrophy of the left ventricle was the underlying cause of the obstruction of the outflow tract. -3 Following Teare's4 description of asymmetrical hypertr...

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Propranolol in management of muscular subaortic stenosis.

Muscular subaortic stenosis (Wigle, Heimbecker, and Gunton, 1962) is one of the names used to describe functional ventricular obstruction which simulates aortic valve stenosis. Other workers (Brock, 1957, 1959; Teare, 1958; Morrow and Braunwald, 1959; Brent et al., 1960; Brockenbrough, Braunwald, and Morrow, 1961; Goodwin et al., 1960) have also emphasized the functional nature of the myocardia...

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Idiopathic ventricular septal hypertrophy causing muscular subaortic stenosis.

D ISCRETE, fixed supravalvular, valvular, and subvalvular forms of aortic stenosis are well recognized clinical entities. In 1957, Brock1 first drew attention to the fact that hypertrophied left ventricular musculature could also lead to obstruction of the left ventrieular outflow tract. He termed this "functional obstruction of the left ventricle" or "acquired aortic subvalvar stenosis." One o...

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Muscular subaortic stenosis. Prevention of outflow obstruction with propranolol.

were performed to induce or increase the functional outflow tract obstruction; 150 pug/kg of propranolol was administered intravenously, and the stimulating maneuvers were repeated. Outflow obstruction was latent (present only with stimulation) in four patients, labile (present intermittently at rest) in five patients, and persistent and severe in two patients. Propranolol abolished or signific...

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ژورنال

عنوان ژورنال: Circulation

سال: 1968

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.38.5.846